Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
Blog Article
1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity related to bortezomib, a proteasome inhibitor Utilized in the cure of multiple myeloma. Its synthesis or examine is very important for making sure the purity and basic safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug used in the remedy of prostate most cancers by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-ten-one): A essential compound from the synthesis of imatinib, a drug that targets certain sorts of most cancers, together with chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats several cancers which include breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are definitely intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their analyze is important for optimizing the creation course of action and ensuring superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilised to take care of breast cancer, and these intermediates are involved in its generation.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Utilized in the treatment PALBOCICLIB intermediate of breast most cancers. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug efficient in treating cancers such as ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and compact cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, that have different programs, including antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for CAS NO. 134790-39-9 variety two diabetes that inhibits the enzyme DPP-4 to manage blood sugar ranges.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved in the synthesis of various gluconic acid derivatives, which can be Employed in food items, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication applied to deal with type 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).